| abstract |
Compounds which in form of pharmaceutical preparations have an antitumor activity higher or comparable to those of conventional drugs, e.g. Daunorubicin and Doxorubicin. The compounds are of the formulan wherein one of R 1 and R 2 represents a hydrogen atom, the other of R, and R 2 represents a formyl, hydroxymethyl or aminomethyl group, and R 3 represents a hydrogen atom or a hydroxy or acyloxy group, and pharmaceutically acceptable acid addition salts of such compounds in which one of R 1 and R 2 represents an aminomethyl group, methods for preparation of said compounds and therapeutical compositions containing same. |