abstract |
The present invention provides aryl ether derivatives of the general formula: <IMAGE> +TR <IMAGE> wherein A is an oxygen atom or the group >N-R1, R1 being a hydrogen atom or a lower alkyl radical, R2 and R3, which can be the same or different, are hydrogen atoms or lower alkyl radicals, R4 is a hydrogen atom or a hydroxyl group, R5 is a hydrogen atom or an acyl radical, R7 is a hydrogen atom, a lower alkyl radical or a lower alkanoyl radical and R8 is a hydrogen atom, a lower alkyl radical, a lower alkoxy radical or a hydroxyl group; and the pharmacologically acceptable salts thereof. The present invention also provides a process for the preparation of these compounds and pharmaceutical compositions containing them. It is also concerned with the use of these compounds for combating allergic diseases. |