abstract |
A composition of matter comprising a Tc-99m labeled antibody and diagnostic kits for forming same are provided. The labeled antibody is anti-human chorionic gonadotropin (anti-hCG) or anit-human chorionic gonadotropin-beta subunit (anti-hCG-β) or a mixture thereof. In diagnostic use, the labeled antibody is administered in physiologically and pharmaceutically acceptable form and its biodistribution is monitored. The labeled antibody will accumulate at cancer sites e.g. tumors that produce human chorionic gonadotropin, human chorionic gonadotropin-like material. comPounds similar or identical to the β-chain of chorionic gonadotropin and mixtures thereof, which bind specifically to anti-hCG and/or anti-hCG-β. |