http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0004723-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a8659631bf38b3a590c0d3edc265492c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-32 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4166 |
| filingDate | 1979-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca5806def32463c08710de846fc7dff8 |
| publicationDate | 1979-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0004723-A1 |
| titleOfInvention | Deoxyhydantoins, processes for their preparation and pharmaceutical compositions containing them |
| abstract | Compounds of the formula (1):wherein:Y is -CH<sub>2</sub>CH<sub>2</sub>-, -CH=CH- or -C=C.n is 1 to 5;R, is hydrogen, or CO<sub>2</sub> R, represents an ester group in which the R, moiety contains from 1 to 12 carbon atoms;R<sub>2</sub> is hydrogen, C<sub>1-4</sub> alkyl, trifluoromethyl, or phenyl;R<sub>3</sub> is hydroxy or protected hydroxy;R<sub>5</sub> is hydrogen, C<sub>1-6</sub> alkyl, phenyl or phenyl C<sub>1-6</sub> alkyl, any of which phenyl moieties may be substituted by one or more halogen, trifluoromethyl, C<sub>1-5</sub> alkyl, C<sub>1-6</sub> alkoxy or nitro groups; andX is CH<sub>2</sub> andR<sub>4</sub> is C,.<sub>s</sub> alkyl, C<sub>3-8</sub> cycloalkyl-C<sub>1-6</sub> alkyl, phenyl-C<sub>1-6</sub> alkyl or naphthyl-C<sub>1-6</sub> alkyl, any of which groups may have one acyclic carbon-carbon bond interrupted by an oxygen atom; hydrogen, C<sub>3-8</sub> cycloalkyl, phenyl or naphthyl, any of which phenyl of naphthyl moieties in R<sub>4</sub> may be substituted by one or more halogen, trifluoromethyl, C<sub>1-6</sub> alkyl, hydroxy, C<sub>1-6</sub> alkoxy or nitro groups; or R<sub>2</sub> and R<sub>4</sub> taken with the carbon atom to which they are joined represent a C<sub>5-8</sub> cycloalkyl group; orX is CS andR<sub>4</sub> is C<sub>1-9</sub> alkyl, C<sub>3-8</sub> cycloalkyl-C<sub>1-6</sub> alkyl, phenyl-C<sub>1-6</sub> alkyl or naphthyl-C<sub>1-6</sub> alkyl, having one acyclic carbon-carbon bond interrupted by an oxygen atom, and in which any phenyl or naphthyl moieties may be substituted by one or more halogen, trifluoromethyl, C<sub>1-6</sub> alkyl, hydroxy, C<sub>1-6</sub> alkoxy or nitro groups; and salts thereof; having similar pharmacological activity to natural prostaglandins, processes for their preparation, intermediates useful in those processes and pharmaceutical compositions containing compounds of the formula (I). |
| priorityDate | 1978-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 78.