| abstract |
A compound of the formulan wherein R,, R 2 and R 3 are the same or different, and each is selected from the group consisting of hydrogen and phenyl groups of the formulan wherein R 4 and R 5 are the same or different and each is. selected from the group consisting of hydrogen, halogen, alkyl having 1; 2, or 3 carbon atoms, alkoxy having 7,2. or 3 carbon atoms, alkoxycarbonyl having 2-7 carbon atoms; and alkylcarbonyl groups having 2-7 carbon atoms; or R 4 and R 5 together form a straight saturated alkylene chain having 3 or 4 carbon atoms and being bound to adjacent positions, i.e. 2,3- or 3,4- in the phenyl ring; provided that one of R 1 and R 2 is a phenyl group of the formula II when R 3 is H; and physiologically acceptable salts and optical isomers thereof; methods for preparation of the compounds, pharmaceutical compositions containing them, and their medicinal use. |