| abstract |
The invention relates to new 17a-aryl or 17a-heteroaryl steroids, their preparation process, their use as a medicament and the pharmaceutical compositions containing them.n n n The compounds of the invention correspond to the formula: R, is a hydrogen or an acyl of 1 to 18 carbons, R 2 an aryl or an aralkyl of 6 to 12 carbons, optionally substituted, or an optionally substituted heteroaryl chosen from the furyl, thienyl, pyridyl and pyrimidyl radicals, the dotted lines represent a possible double bond, and or A is an oxo and B a hydrogen, or A a β-hydroxyl and B a hydrogen or a halogen, or A and B form a double bond 9 (11). Compounds I are anti-inflammatory. |