| abstract |
Compounds of the formulan wherein the dotted line represents an optional double bond and Ar represents the groupn wherein Y is bound in the 2-, 3- or4-position and represents a lower alkyl or lower alkoxy group, a halogen, a trifluoromethyl group or an amino, mono-or di-lower alkylamino group, or Ar represents a pyridyl group bound in the 2-, 3- or4-position, X represents hydrogen, a lower alkyl or lower alkoxy group, a halogen, a trifluoromethyl group or an amino, mono- or di-lower alkylamino group, R represents a lower alkyl group, and R represents hydrogen or a lower alkyl group, or a therapeutically acceptable acid addition salt thereof, or a bioprecursor thereof. n The compounds are prepared by various methods; pharmaceutical compositions containing the compounds are described. |