http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EC-SP993070-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-04 |
| filingDate | 1999-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bbe4cdcb9f08d234ac6eacfd2887c0d5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07bce4252cdd9c961c1804ced781b529 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45f555b7c7f18538bb5ff407d04e03ad http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fced96358a3ad58a70a97ca428f5e4f4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01f2389afaacb76878c171837ef7a28a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7c77d431c2b5e31cde5e07f53f21793 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de647462cb5ecbd24eee533a0f73cfca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ccb422961953749f3fcfa1016870ae12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_27d8663d5f5a4090ba6292995d42e65d |
| publicationDate | 1999-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EC-SP993070-A |
| titleOfInvention | HIGH-AFFINITY LEAGUES FOR THE NOCICEPTINE ORL 1 RECEPTOR |
| abstract | Novel compounds of formula (graph), or a pharmaceutically acceptable salt or solvate thereof in which: the dotted line represents an optional double bond; X1 is optionally substituted H, alkyl, cycloalkyl, aryl, heteroaryl, heterocycloalkyl or heterocyclyl; X2 is H, -CH =, -CN, amino, alkyl or optionally substituted aryl; or X1 or X2 together form an optionally benzofused spiro heterocyclyl group. R1, R2, R3 and R4 are independently H or alkyl, or (R1 and R4) or (R2 and R3) or (R1 and R3) or (R2 and R4) together can form an alkylene bridge of 1 to 3 carbon atoms ; Z1 is optionally substituted alkyl, aryl, heteroaryl, cycloalkyl or heterocycloalkyl or -CO2 (alkyl or substituted amino) or CN, Z2 is H or Z1; Z3 is H or alkyl; or Z1, Z2 and Z3 together with the carbon to which they are attached form saturated or unsaturated bicyclic rings; Pharmaceutical compositions including the same and the use of said compounds as inhibitors, nociceptin receptors useful for the treatment, anxiety, cough, asthma, depression and alcohol abuse. |
| priorityDate | 1999-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.