http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EC-SP992913-A
Outgoing Links
Predicate | Object |
---|---|
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D309-14 |
filingDate | 1999-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4eace7202564e4e1138490865937bbc1 |
publicationDate | 1999-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EC-SP992913-A |
titleOfInvention | ACID HYDROXAMIDES (4- ARYL SULFONYLAMINE) - TETRAHYDROPIRAN -4- CARBOXYLIC |
abstract | A compound of formula (graph), in which Q is as defined above, which is useful in the treatment of a disorder selected from the group consisting of arthritis (including osteoarthritis and rheumatoid arthritis), inflammatory bowel disease, disease of Crohn's disease, emphysema, chronic obstructive pulmonary disease, Alzheimer's disease, organ transplant toxicity cachexia, allergic reactions, allergic contact hypersensitivity, cancer, ulceration of tissues, restenosis, periodontal disease, epidermolysis bullosa, osteoporosis, lack of firmness of artificial joint implants, atherosclerosis (including atherosclerotic plaque rupture), aortic aneurysm (including abdominal aortic aneurysm and cerebral aortic aneurysm), congestive heart failure, myocardial infarction, cerebrovascular accident, cerebral ischemia, head injury, spinal cord injury spinal, neurodegenerative disorders (acute and c autoimmune disorders, Huntington's disease, Parkinson's disease, migraine, depression, peripheral neuropathy, pain, cerebral amyloid angiopathy, nootropic or cognitive enhancement, amyotrophic lateral sclerosis, multiple sclerosis, ocular angiogenesis, corneal injury, macular degeneration, abnormal healing of wounds, burns, diabetes, tumor invasion, tumor growth, tumor metastasis, corneal burns, scleritis, AIDS, septicemia and septic shock. Furthermore, the compounds of the present invention can be used in combination therapy with non-steroidal anti-inflammatory drugs (NSAIDs) and conventional pain relievers, and in combination with cytotoxic drugs such as adriamycin, daunomycin, cis-platinum, etoposide, taxol, taxater and other alkaloids such as Vincristine, in the treatment of cancer. |
priorityDate | 1999-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.