http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EC-SP992850-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-16 |
| filingDate | 1999-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a2510e6b5a23ae823025f52338cba79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7da3d0b6f145b5241a0b43c1dae4aa9b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_566b3ecc3e8b16800ac01c22d2f5175d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_79c4e979d1f033feb3b1ae332e6b07ba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e695d4b0a5726b210f42857a50d43eb8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42c88752523cae1f733b5f0c09b26eba |
| publicationDate | 1999-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EC-SP992850-A |
| titleOfInvention | CYCLE DERIVATIVES N-ACIL OF AMINE |
| abstract | The invention relates to compounds represented by the general formula (I): (graph), in which Ar means an aryl group or a heteroaryl group which may have a substituent group selected from the group consisting of a halogen atom, a group lower alkyl and lower alkoxy group; R1 signifies a C3-C6 cycloalkyl group, which is substitutable with a fluorine atom; R2 and R4 signify hydrogen atoms, groups represented by - (A1) m -NH-B or the like; R3 and R5 signify hydrogen atoms, C1-C6 aliphatic hydrocarbon groups or the like which are substitutable with a lower alkyl group (s); n means 0 or 1; and X means an oxygen atom or a sulfur atom]. Compounds according to the invention, because they not only have potent selective antagonistic activity against M3 muscarinic receptors, but also exhibit excellent oral activity, durability of action and pharmacokinetics are very useful as safe and effective drugs against respiratory, urinary diseases, and digestive and have very few adverse side effects. |
| priorityDate | 1999-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 18.