http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EC-SP982799-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 |
| filingDate | 1998-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_101d9380fbdcf101d2777bd154d1fdcc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d18a8175e02bb9332b42827a4cf8afd8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e647e5d3e2a9c2c0bc84f2e47d1661b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca24e4e0d645f1244cf8422402a0292d |
| publicationDate | 1999-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EC-SP982799-A |
| titleOfInvention | SODIUM INHIBITORS EXCHANGE OF ACIL GUANIDINE PROTONS AND METHOD OF USE |
| abstract | Acyl guanidines are provided which are proton / sodium exchange inhibitors (NHE), which have the structure (graph), where n is 1 to 5; X is N or C-R5 where R5 is H, halo, alkenyl, alkynyl, alkoxy, alkyl, aryl or heteroryl; and R1, R2, R3 and R4 are as defined herein, and wherein X is N, N1 is preferably aryl or heteroaryl, and are useful as antianginal and cardioprotective agents. In addition, a method is provided to prevent or treat angina pectoris, cardiac dysfunction, myocardial necrosis, and arrhythmia using the above acyl guanidines. |
| priorityDate | 1998-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 18.