http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EC-SP951610-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-02 |
| filingDate | 1995-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f697a0e7b94c8ca169b97236c99d5a92 |
| publicationDate | 1997-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EC-SP951610-A |
| titleOfInvention | TACHYCININ ANTAGONISTS |
| abstract | Compounds of formula I (graph) are provided, wherein R1 is mono or disubstituted phenyl, n is zero or 1, X1 is oxygen, sulfur or = NCN, X2 and X3 are each independently oxygen or sulfur, R2 is hydrogen or methyl, R3 is phenyl, halo-substituted phenyl, 2-naphthyl, IH-indole-3-yl or 1-methyl-indole -3-yl, Z is N (CH3) -o -CH2-, R4 is phenyl, 3 , 65 bis (trifluoromethyl) phenyl or pyridyl, and R5 is hydrogen, phenyl, 3,5-bis (trifluoromethyl) phenyl or pyridyl, whereby, when X3 is sulfur, Z is -N (CH3) -, and a sakl of acid addition thereof having antagonist activity for tachykinin, and are useful as substances pharmaceutically, for example for the treatment of pain. |
| priorityDate | 1995-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.