| abstract |
Compounds of formula (I) (SEE FORMULA IN THE TECHNICAL REPORT) in which: Ak1 represents an alkyl chain, X represents -(CH2)m-, -CH(R)-, -N(R)-, -CH2- N(R)-, -N(R)-CH2- or -CH2-N(R)-CH2-, m and R are as defined in the description, R1 and R2 each represent H when X represents -( CH2)m-, -CH(R)-, -N(R)-, -CH2-N(R)- or –N(R)-CH2-, or together form a bond when X represents -CH2-N (R)-CH2-, R3 represents NH2, Cy-NH2, Cy-Ak3-NH2 or piperidin-4-yl, Cy and Ak3 are as defined in the description, R4 and R5, identical or different, each represent one H or F, their optical isomers, as well as their addition salts to a pharmaceutically acceptable acid. Medicines. |