abstract |
A pharmaceutical reservoir comprising (i) 5-fluoro-2 - [[(1S) -1- (5-fluoro-2-pyridyl) ethyl] amino] -6 - [(5-isopropoxy-1H-pyrazole-3- il) amino] pyridin-3-carbonitrile or its pharmaceutically acceptable salt, as a pharmaceutical agent (PA) and (ii) a polymer that degrades to create an acid microclimate, where PA is released from the polymer after polymer degradation. |