| abstract |
The present invention relates to new crystalline, pharmaceutically acceptable and water-soluble addition salts of (i) an amine containing one or more hydroxyl and / or carboxylic groups with (ii) aminonicotinic acid derivatives of the formula wherein Ra, Rb, Rc and Rd independently represent groups selected from hydrogen atoms, halogen atoms, C1-4 alkyl groups which may be optionally substituted with 1, 2 or 3 substituents selected from halogen atoms and hydroxy groups, and C1-4 alkoxy groups which may optionally be substituted with 1, 2 or 3 substituents selected from halogen atoms and hydroxy groups, and their pharmaceutically acceptable solvates. |