http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EC-SP044984-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b8be6a6c990669567cc455d32b00535e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D489-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D489-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D489-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D489-08 |
| filingDate | 2004-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6599801b36fc4da1bea6d70eb81d4df9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7318186e8259afa93675cc3a8236bb23 |
| publicationDate | 2004-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EC-SP044984-A |
| titleOfInvention | OXIDATION OF THE C-14 DERIVATIVES OF MORPHINE |
| abstract | The present invention relates to a process for the preparation of a derivative of 14 hydroxymorphorfinone of formula IV, which comprises the reaction of the compound of formula III with a cobalt (II) oxidant in the presence of a soft base and air or oxygen as co-oxidant; wherein R1 is (1C-7C) alkyl, optionally substituted by one or more chlorines, by butenyl, vinyl, benzyl, phenyl or naphthyl; and R2 is benzyl or benzyl substituted by one or more substituents of the group (1C-6C) alkoxy or benzyl substituted by one or more halogens. The process is very suitable for the production of noroxymorphone. |
| priorityDate | 2001-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.