abstract |
The present invention relates to a method of treatment or prevention of cluster headache, migraine or headache, method comprising co-administration of a therapeutically effective amount of compound A = 1- [N2- [3,5-Dibromo-N - [[4- (3, 4-dihydro-2 (! H) -oxoquinazolin-3-yl) -1-piperidinyl] carbonyl] -D-tyrosyl] -L-lysyl] -4- (4-pyridinyl) - piperazine [BIBN4096BS] or one of its physiologically acceptable salts and a therapeutically effective amount of a second active antimigraphic drug, particularly sumatriptan, zolmitripan or diidroergotamine or one of its physiologically acceptable salts, as well as the corresponding pharmaceutical compositions and their preparation. |