abstract |
The present invention relates to the use of known imidazotriazinones substituted at position 2 phenyl with short alkyl radicals, unbranched at position 9 and with cGMP-PDE inhibitory properties for the preparation of medicaments for the treatment of heart failure, psoriasis , female infertility, cancer, diabetes, eye diseases such as glaucoma, stomach movement disorders, cystic fibrosis, premature contractions, pulmonary hypertension, bladder diseases, prostatic hyperplasis, nitrate-induced tolerance, preeclampsia, alopecia, Parkinson's disease, pain, tinnitus or renal syndrome. |