http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EC-SP003831-A
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-62 |
filingDate | 2000-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_693ee6f21e872c18b0e6a265cbe1e2a5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_087ddbd0ce25bf1632c26cdf7d86c14e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b693965ccec87150238d94c8d12621e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d81a97bba705a62055a10feed74a19cc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0aee62a8743ea1269bdd64b3abcb164 |
publicationDate | 2001-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EC-SP003831-A |
titleOfInvention | COMPOSITIONS OF POLYPEPTIDES WITH IMPROVED STABILITY |
abstract | The present invention provides means for improving the chemical stability of parenteral aqueous pharmaceutical compositions comprising a polypeptide and glycerin. Reactive aldehydes are identified in commercial glycerin and means are provided to reduce the level of said reactive aldehydes in glycerin and a clear linear relationship between the level of reactive aldehydes of glycerin and the chemical stability of compositions comprising a polypeptide and glycerin are demonstrated. . The invention includes aqueous compositions comprising a polypeptide and glycerin and having improved chemical stability compared to previously known compositions. |
priorityDate | 2000-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Predicate | Subject |
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isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID753 http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419483452 |
Total number of triples: 16.