http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EA-201992226-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-542 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-58 |
| filingDate | 2018-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EA-201992226-A1 |
| titleOfInvention | NPRA AGONISTS, COMPOSITIONS AND THEIR USE |
| abstract | The present invention discloses a derivative of a natriuretic peptide of formula (I) and compositions comprising a derivative of a natriuretic peptide of formula (I), where z is 1, x is an integer from 2 to 4, and y is 3; or z represents 0, x represents an integer from 0 to 4, and y represents an integer from 1 to 3; fatty acyl contains from 12 to 24 (for example, from 12 to 18) carbon atoms; B is lysine or arginine; G represents glycine; NP is a natriuretic peptide; if present (fatty acyl) - covalently bind to the N-terminus in (B); (fatty acyl) - (B) - covalently linked to the N-terminus in (G); and (fatty acyl) - (B) - (G) - is covalently linked to the N-terminus in NP. The natriuretic peptide derivative according to the disclosure and its composition can be used in the treatment of diseases such as hypertension, vascular congestion and heart disease. |
| priorityDate | 2017-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.