http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EA-201892170-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y302-0102 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-2408 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0095 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-26 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-26 |
| filingDate | 2017-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EA-201892170-A1 |
| titleOfInvention | COMPOSITIONS CONTAINING RECOMBINANT ACID α-GLUCOSIDASE |
| abstract | Pharmaceutical formulations containing recombinant acid α-glucosidase are presented, where recombinant acid α-glucosidase is obtained by expression in Chinese hamster ovary (CHO) cells and is characterized by an increased content of N-glycan units bearing one or two mannose-6-phosphate residues, comparison with the content of N-glycan units bearing one or two mannose-6-phosphate residues in alglucosidase-alpha; at least one buffer selected from the group consisting of citrate, phosphate, and combinations thereof; and at least one excipient selected from the group consisting of mannitol, polysorbate 80, and combinations thereof, where the composition is characterized by a pH ranging from about 5.0 to about 7.0. Also presented are methods for treating Pompe's disease using data from pharmaceutical formulations. |
| priorityDate | 2017-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.