http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EA-201691629-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-233 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-47 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2015-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EA-201691629-A1 |
| titleOfInvention | CRYSTAL SOLID FORMS N- {4 - [(6,7-DIMETOXYHINOLIN-4-IL) OXY] PHENYL} -N '- (4-Fluorofenyl) CYCLOPROPAN-1,1-DICARBOXAMIDA, GETTING CHANGES |
| abstract | The present invention relates to new crystalline solid forms of the chemical compound N- {4 - [(6,7-dimethoxyquinolin-4-yl) oxy] phenyl} -N '- (4-fluorophenyl) cyclopropane-1,1-dicarboxamide (Compound 1 ) and its solvates, including hydrates, which are applicable for the treatment of cancer. Also describes pharmaceutical compositions containing crystalline solid forms, and methods for producing crystalline solid forms, as well as methods for their use for the treatment of cancer, in particular thyroid cancer, prostate cancer, hepatocellular cancer, kidney cancer and non-small cell carcinoma of the lung. Crystalline solid forms can be used to obtain the L-malate salt of cabozantinib. |
| priorityDate | 2014-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 19.