http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EA-201591918-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09B23-0025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-5456 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09B69-008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09B23-141 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09B23-0008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09B69-001 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-5449 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-5442 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-662 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-54 |
| filingDate | 2014-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-02-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EA-201591918-A1 |
| titleOfInvention | DERIVATIVES OF TAMOXIFEN FOR THE TREATMENT OF NOVOLOGICAL FORMATIONS, ESPECIALLY WITH A HER2 HER2 PROTEIN |
| abstract | The aim of the present invention is new mitochondrial E / Z isomers of aliphatic triphenylphosphonium tamoxifen derivatives, where the aliphatic chain is alkyl or alkenyl, and their corresponding tertiary amine salts and / or their mixture (MitoTAX). Alkyltriphenylphosphonium tamoxifen derivatives have the general formula (I), where n = 8-12 and Z is selected from the group of organic salts or inorganic salts. Alkenyltriphenylphosphonium tamoxifen derivatives have the general formula IA, where n = 6-10 and Z has the above value. These compounds are applicable for the treatment of tumors, especially tumors with high levels of the HER2 protein. The medicament for treating neoplasms of the present invention contains at least one E / Z isomer of aliphatic triphenylphosphonium tamoxifen derivatives of general formula (I) and / or IA or their corresponding tertiary amine salts. |
| priorityDate | 2013-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.