| abstract |
The invention relates to derivatives of N- (2,3-dihydro-1H-pyrrolo [2,3-b] pyridin-5-yl) -4-quinazolinamine and N- (2,3-dihydro-1H-indol-5-yl ) -4-quinazolinamine of formula (I) wherein R, R, R, R, R, R and A have the meaning given in the claims. The compounds of the present invention are used as PERK inhibitors. The present invention also relates to methods of producing such compounds, pharmaceutical compositions containing said compounds as an active ingredient, as well as the use of said compounds as a medicine. |