http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EA-201590252-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-506 |
| filingDate | 2013-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EA-201590252-A1 |
| titleOfInvention | ARYLETHINYLPYRIMIDINES |
| abstract | The present invention relates to ethynyl derivatives of the formula I wherein R 1 is hydrogen or halogen; R is C-alkyl or - (CH) -O-CH; n is 2 or 3; m is 1 or 2; or their pharmaceutically acceptable acid addition salts, racemic mixtures or the corresponding enantiomers, and / or optical isomers, and / or stereoisomers. The compounds of general formula I were found to be allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5) with improved properties for the treatment of schizophrenia, cognitive disorders, X-linked chromosome syndrome or autism. |
| priorityDate | 2012-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID783 http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID425193155 http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID458392875 |
Total number of triples: 19.