http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EA-201490535-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-549 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-22 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00 |
| filingDate | 2012-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2014-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EA-201490535-A1 |
| titleOfInvention | Pyrrolbenzodiazepine |
| abstract | The compound of the formula I, where R is the formula II, where X is selected from the group consisting of OH, SH, COH, COH, N = C = O, NHNH, CONHNH, NHR, where R is selected from the group consisting of H and C1-6 alkyl; R, R and R are independently selected from H and unsubstituted C1-6 alkyl; and either R is selected from the group consisting of (ia) a Caryl group optionally substituted by one or more substituents selected from the group consisting of halogen, nitro, cyano, ether, C1-6 alkyl, Cheterocyclyl, and bis-hydroxy-C1-6 alkylene; (ib) C saturated aliphatic alkyl; (ic) Saturated cycloalkyl; (id) where each of R, R and R is independently selected from H, C saturated alkyl, Salkenyl, Salkinyl and cyclopropyl, where the total number of carbon atoms in the group R is not more than 5; (ie) where one of R1 and R1 is H and the other is selected from phenyl, where phenyl is optionally substituted with a group selected from halogen, methyl, methoxy; pyridyl and thiophenyl; and (if) where R is selected from H; C saturated alkyl; Salkenil; Calkinilla; cyclopropyl; phenyl, where phenyl is optionally substituted with a group selected from halogen, methyl, methoxy; pyridyl and thiophenyl; and R and R are independently selected from H, R, OH, OR, SH, SR, NH, NHR, NRR ', nitro, MeSn, and halogen; where R and R 'are independently selected from the optionally substituted C1-6 alkyl, C2 heterocyclyl and Saryl groups; R is selected from H, R, OH, OR, SH, SR, NH, NHR, NHRR ', nitro, MeSn and halogen; either (a) R 5 is H and R is OH, OR, where R 2 is C1-6 alkyl; (b) R and R form a nitrogen-carbon double bond between the nitrogen and carbon atoms to which they are attached; or (c) R 2 is H and R 3 is SOM, where z is 2 or 3 and M is a monovalent pharmaceutically acceptable cation; R "is a C1-6 alkylene group whose chain may be interrupted by one or more heteroatoms and / or aromatic rings; Y and Y 'are selected from O, S or NH; |
| priorityDate | 2011-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.