http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EA-201391296-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4985 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4985 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 |
| filingDate | 2012-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2014-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EA-201391296-A1 |
| titleOfInvention | DERIVATIVES 3,4-DIHYDROPYRROLO [1,2-a] PIRAZIN-1-ILAMINA, SUITABLE AS BETA SECRETASE INHIBITORS (BACE) |
| abstract | The invention relates to new derivatives of 3,4-dihydropyrrolo [1,2-a] pyrazin-1-ylamine as beta-secretase inhibitors, also known as an enzyme that cleaves the amyloid precursor at the beta site, BACE, BACE1, Asp2 or memapsin2. The invention is also directed to pharmaceutical compositions containing such compounds, to methods for preparing such compounds and compositions, and to the use of such compounds and compositions for the prevention and treatment of disorders involving beta-secretase, such as Alzheimer's disease (AD), mild cognitive impairment, extinction, dementia, dementia with Levi bodies, Down syndrome, dementia associated with stroke, dementia associated with Parkinson's disease, or dementia associated with amyloid beta. |
| priorityDate | 2011-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.