http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EA-201390571-A1
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F9-0008 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-525 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F9-0026 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-325 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-0428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-0448 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N5-0613 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-0436 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-044 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-0492 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F9-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61N1-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61N1-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F9-00 |
filingDate | 2011-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2013-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EA-201390571-A1 |
titleOfInvention | DEVICE AND METHOD FOR FEEDING RIBOFLAVIN IN THE CORNETRY BY IONOPHORESIS FOR THE TREATMENT OF KERATOCONUS |
abstract | A device for ocular iontophoresis for supplying an ionized drug solution, such as a riboflavin solution, to the cornea, containing the following interacting elements: a reservoir (8) containing a riboflavin solution and made with the possibility of simple placement on the eye; active electrode (2) located in the reservoir (8) or on the reservoir (8); a passive electrode adapted to be placed on the skin of the patient's body, preferably in close proximity to the eyes, for example, on the forehead, cheek or neck; means (10) irradiating the surface of the cornea with a suitable radiation, such as ultraviolet radiation (UV radiation), to cross-link the cornea after administration of the drug or riboflavin; wherein said reservoir (8) and said active electrode (2) are transparent to UV and / or visible and / or infrared radiation. A method of supplying an ionized drug solution, for example, a riboflavin solution, into the cornea for the treatment of keratoconus or other corneal disease accompanied by ectasia, or for strengthening the corneal stroma by means of an ocular iontophoresis device according to claims 1-24, characterized in that it comprises the steps of placing the specified device on the eye intended for treatment, and the device contains a reservoir with a solution of riboflavin; the solution is set in motion by means of a cathodic current supplied for 0.5 to 5 minutes, with a force not exceeding 2 mA; irradiate, immediately after cessation of the current supply, the surface of the cornea with UV radiation for 5 to 30 min with a power of 3 to 30 mV / cm, thus performing cross-linking of the cornea |
priorityDate | 2011-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.