http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EA-201201336-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 |
| filingDate | 2012-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2014-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EA-201201336-A1 |
| titleOfInvention | Recombinant plasmid DNA pFK3, provides a synthesis of recombinant peptides RL3, is an analogue of kappa-casein FRAGMENTS OF HUMAN RECOMBINANT STRAIN OF BACTERIA ESCHERICHIA COLI XL1-BLUE / pFK3 and recombinant peptides RL3 - ANALOG FRAGMENTS of kappa-casein A person with apoptotic activity against cancer cells |
| abstract | The invention relates to recombinant plasmid DNA with fragments of human kappa-casein, a recombinant Escherichia coli strain of the peptide analogue of human kappa-casein, which has apoptotic activity against tumor cells and the recombinant peptide, an analogue of human kappa-casein, and can be used in biotechnology. Recombinant plasmid DNA pFK3 provides a higher synthesis of recombinant peptide RL3, which is an analogue of the human kappa-casein fragment and has a molecular weight of 2.41 MDa and a size of 3647 bp. The Escherichia coliXL1-Blue / pFK3 recombinant bacterial strain was deposited at the Inter-Institute Center for Collective Use of the Siberian Branch of the Russian Academy of Sciences "Collection of Extremophilic Microorganisms and Type Cultures" under No. EMTC 1346 and is a producer of peptide RL3, an analogue of human kappa-casein, having a human activity with a human subject, having a human activity, a human having an optically active band, RL3 peptide, an individual with a human activity, having a human subject with an apoptotic profile. . In addition, the obtained recombinant peptide RL3 is an analogue of the human kappa-casein fragment, having a molecular weight of about 10 kDa, consisting of a methionine residue, a human kappa-casein fragment with 31 to 102 amino acid residue and a C-terminal histidine tract and having apoptotic activity with respect to to cancer cells. |
| priorityDate | 2012-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.