| abstract |
The application describes CCR1 receptor antagonists of formula (I) in which X is nitrogen or CR; Ar is a carbocycle, heteroaryl or heterocyclyl, each of which is optionally substituted with 1-3 R groups; Ar is a carbocycle, heteroaryl or heterocyclyl, each of which is optionally substituted with 1-3 R groups; cyclic G is carbocycle or heterocyclyl, each of which is optionally substituted with 1-2 R groups; R is hydrogen, C — C alkyl, or C — C alkoxy-C — C alkyl. The application also describes compositions, methods for the preparation and use of compounds of formula (I). |