| abstract |
New sirtuinmodulating compounds and methods of their application are proposed. Sirtuin-modulating compounds can be used to increase the cell life cycle and to treat and / or prevent a large number of diseases and disorders, including, for example, diseases or disorders associated with aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, disorders blood coagulation, inflammation, cancer and / or hyperemia, as well as diseases or disorders in which mitochondrial activity is required to be increased. Also provided are compositions comprising a sirtuin modulating compound in combination with another therapeutic agent. |