| abstract |
New methods for treating and / or reducing the likelihood of acquired symptoms or diseases due to menopause in postmenopausal women, in particular osteoporosis, vaginal atrophy and dryness, hypogonadism, low libido, skin atrophy, collagenosis, urinary incontinence, breast cancer, endometrial cancer, ovarian cancer, are described. and cancer of the uterus, hot flashes, loss of muscle mass, insulin resistance, fatigue, loss of energy, aging, physical symptoms of menopause in sensitive warm-blooded animals, including humans, include including the introduction of the precursor of sex steroid hormones. This method provides new methods for administering and dosing dehydroepiandrosterone (DHEA) to use the positive androgenic effects in the vaginal layers of lamina propia (the lamina propria) and / or the muscularis layer (muscularis lamina) without causing undesirable systemic estrogenic effects to avoid the risk of cancer breast and uterine cancer. Pharmaceutical compositions for delivering the active ingredient (s) are useful in this invention. |