abstract |
The present invention relates to salts of 3- (3-amino-2- (R) -hydroxypropyl) -1- (4-fluorophenyl) -8- (8-methylnaphthalen-1-ylmethyl) -1,3,8-triazaspiro [4 , 5] decan-4-one, pharmaceutical compositions containing them, and their use in the treatment of disorders and conditions modulated by NRA, such as depression, anxiety, alcohol abuse, etc. The present invention further relates to methods for producing 3- (3-amino-2- (R) -hydroxypropyl) -1- (4-fluorophenyl) -8- (8-methylnaphthalen-1-ylmethyl) -1,3,8-triazaspiro [4,5] decan-4-one and its corresponding salts. |