http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EA-200900708-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-381 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-20 |
| filingDate | 2007-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2009-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EA-200900708-A1 |
| titleOfInvention | METHOD OF CLEANING (S) -N-METHYL-3- (1-NAFTYLOXY) -3- (2-THIENYL) PROPYLAMINE HYDROCHLORIDE (DULOXETHINE) |
| abstract | The method of purification of (S) -N-methyl-3- (1-naphthyloxy) -3- (2-thienyl) propylamine hydrochloride of the formula I, which includes aquatic environment; (b) the conversion of the base of a substance of formula (I) into crystalline hydrochloride by the action of hydrochloric acid or gaseous HCl in an organic solvent or mixture of organic solvents. The method of purification of (S) -N-methyl-3- (1-naphthyloxy) -3- (2-thienyl) propylamine hydrochloride of formula (I), including the dissolution of this substance in the minimum amount of methanol containing from 0 to 50% water, and converting it back to solid (precipitation) by adding a less polar solvent. |
| priorityDate | 2006-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 20.