http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EA-200802385-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-567 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-0081 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-567 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J1-00 |
| filingDate | 2007-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2009-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EA-200802385-A1 |
| titleOfInvention | CRYSTAL FORMS 11β- (4-ACETYLPHENYL) -20,20,21,21,21-PENTAFTOR-17-HYDROXY-19-NOR-17A-PREGNA-4,9-DIEN-3-SHE |
| abstract | The present invention relates to crystalline forms of 11β- (4-acetylphenyl) -20,20,21,21,21-pentafluoro-17-hydroxy-19-nor-17α-pregna-4,9-dien-3-one. The invention relates in particular to two crystalline insolvate / non-hydrate forms of this compound, polymorphs I and II. In addition, the present invention also relates to crystalline solvates, for example the methanol and ethanol solvates of 11β- (4-acetylphenyl) -20,20,21,21,21-pentafluoro-17-hydroxy-19-nor-17α-pregna-4, 9-dien-3-one as a precursor for obtaining these two polymorphs I and II. Describes a method for producing polymorph I by substitution crystallization or by powdering. The choice of solvent for the latter before the formation of the insolvate form can be based on differences in the cleaning behavior of the individual solvates of 11β- (4-acetylphenyl) -20,20,21,21,21-pentafluoro-17-hydroxy-19-nor-17α-pregna- 4,9-dien-3-one. Polymorph I according to the invention is particularly suitable for the manufacture of medical products. |
| priorityDate | 2006-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.