http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EA-200702377-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4192 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D249-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4192 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-04 |
| filingDate | 2006-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2008-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EA-200702377-A1 |
| titleOfInvention | DERIVATIVES OF BENZOTRIAZOLE AS ANTAGONISTS OF CANNABINOID RECEPTOR |
| abstract | This invention relates to the group of benzotriazole derivatives below, which are effective modulators of the cannabinoid CB receptor (known as antagonists or inverse agonists), effective in the treatment of obesity, mental and neurological disorders, as well as other diseases in which neuronal transmission of cannabinoid-CB is involved (Current Opinion in Drug Discovery & Development 2004 7 (4): 498-506), their pharmaceutically acceptable acid addition salts and stereoisomeric forms, where R is hydrogen, halogen, trifluoromethyl , C1-6alkyl, C1-6alkyloxy or C1-6alkyloxycarbonyl-; R 1 is hydrogen, phenyl, Cycloalkyl or C 1-6 alkyl optionally substituted with Ar; R 1 is hydrogen, hydroxyl or C 1-6 alkyl; Ar is phenyl or phenyl substituted with up to three substituents; and Het is a monocyclic 5- or 6-membered partially saturated or aromatic heterocycle selected from furanyl, thienyl, pyrrolyl, oxazolyl, thiazolyl, imidazolyl, pyrazolyl, isoxazolyl, isothiazolyl, oxadiazolyl, triazolyl, thiadiazolyl, pyridinyl pyrimidinyl , pyridazinyl, 2H-pyranyl or 4H-pyranyl, wherein said heterocycle is optionally substituted with C1-6alkyl. |
| priorityDate | 2005-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.