http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EA-200501325-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-675 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7076 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7072 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7076 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7072 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-675 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-04 |
| filingDate | 2004-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2006-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EA-200501325-A1 |
| titleOfInvention | ANALOGUES OF ANTI-VIRAL NUCLEOSIDES AND METHODS OF TREATING VIRAL INFECTIONS, IN PARTICULARITY OF HIV INFECTIONS |
| abstract | The present invention relates to new compounds in accordance with the general formulas (I, II, III, IV or V), in which B is a nucleoside base in accordance with the structure of formula (VI); R is H, F, Cl, Br, I, C 1 -C 6 alkyl (preferably CH), —C≡N, –C≡C-R, formula (VII); X is H, C 1-4 alkyl (preferably CH), F, Cl, Br or I; Z is O or CH with the proviso that Z is CH and not O when the compound corresponds to the general formula II; R + is -C≡C-H and R is a H or phosphate, diphosphate, triphosphate or phosphotriester group; R is H, acyl group, C 1 -C 6 alkyl or ether group; R is H, an acyl group, a C 1 -C 6 alkyl or ester group, a phosphate, diphosphate, triphosphate, phosphodiester group, or a group of formula (VIII) or formula (IX); Nu is the radical of a biologically active antiviral compound so that the amino group or hydroxyl group of the indicated biologically active antiviral compound forms a phosphate, phosphoramidate, carbonate or urethane group with an adjacent part; R is H or C 1 C1-6 alkyl or ester group, preferably a C1-6 alkyl group; k is 0-12, preferably 0-2; R is selected from C 1 -C 6 alkyl (preferably CH), - (CH) -C≡C-R, formula (X) or formula (XI) R and R are independently selected from H, F, Cl, Br or I; R and R + are independently selected from H, F, Cl, Br, I, OH, C 1 C1-6 alkyl, preferably CH), - (CH) -C≡CR, formula (XII) or formula (XIII) with the proviso that R and R are H; Is H, F, Cl, Br, I or -C-C1-6 alkyl, preferably H or CH; Y is H, F, Cl, Br, I or -C-C1-6 alkyl, preferably H or CH; and n is 0, 1, 2, 3, 4 or 5, preferably 0, 1 or 2; and their anomers, pharmaceutically acceptable salts, solvates, or their polymorphs. The international application was published along with an international search report. |
| priorityDate | 2003-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.