http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EA-200500792-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-88 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-88 |
| filingDate | 2003-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2005-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EA-200500792-A1 |
| titleOfInvention | METHOD OF OBTAINING CARVEDILOLA |
| abstract | The invention provides a new method for the preparation of carvedilol for pharmaceutical use. In the synthesis of carvedilol, the reaction of 4- (oxiran-2-ylmethoxy) -9H-carbazole (II) with 2- (2-methoxyphenoxy) ethylamine (IV) salts in the presence of a base in an alcohol containing from C2 to C5 carbon atoms solvent at elevated temperature. After processing the crude reaction mixture, crude carvedilol is obtained, which is purified by crystallization from ethyl acetate with the addition of activated carbon, and the final substance is obtained by crystallization from ethyl acetate. The international application was published together with an international search report. |
| priorityDate | 2002-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.