| abstract |
The present invention relates to pharmaceutical preparations comprising, as active compounds, 3-azabicyclo [3.2.1] octane derivatives of general formula (I) and / or their dimers of general formulas (II) and (III), which act as human neurotrophin agonists . In addition, such compounds of formulas (I), (II) and (III) are useful for the treatment of diseases in which there is a defect in the function of neurotrophins, especially nerve growth factor (NGF), such as neurodegenerative diseases of the central nervous system (CNS), acquired immunodeficiency due to reduced NGF bioavailability or pathological conditions in which the process of neoangiogenesis stimulation is beneficial. The international application was published along with an international search report. |