| abstract |
The purpose of the present invention is to provide an antagonist against CRF receptors, which is effective as a therapeutic or prophylactic agent for diseases in which CRF is believed to be involved, such as depression, anxiety, Alzheimer's disease, Parkinson's disease, Huntington's chorea, eating disorders , hypertension, gastric diseases, drug dependence, epilepsy, cerebral infarction, cerebral ischemia, cerebral edema, external head injury, inflammation, disease Relating to immunity, alopecia, irritable bowel syndrome, sleep disorders, epilepsy, dermatitis, schizophrenia, etc. A pyrrolopyrimidine or pyrrolopyridine derivative substituted by a cyclic amino group represented by the following formula [I]: having high affinity for CRF receptors and being effective against diseases in which CRF is said to be involved. The international application was published together with an international search report. |