| abstract |
A method of stimulating osteogenesis is disclosed, including the administration of an effective amount of 1) an oligomeric complex of one or more RANKL, RANKL hybrid protein, its analogue, derivative or mimetic, 2) an osteogenic compound capable of increasing the activity of one or more intracellular proteins in osteoblasts or in precursors of osteoblasts, this activity is a sign of bone formation, or 3) an osteogenic compound capable of inactivating one or more phosphatase in osteoblasts or in the precursors of osteoblasts astov, while this inactivation is a sign of bone formation. This method can also be used to treat a disease or condition manifested, at least in part, in bone loss, including administering to a patient a pharmaceutical composition comprising an oligomeric complex or an osteogenic compound described in this application. The international application was published along with international search. |