http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EA-200200018-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/H01L21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 |
| filingDate | 2001-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2002-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EA-200200018-A1 |
| titleOfInvention | METHOD OF OBTAINING PURE CYTALOPRAMA |
| abstract | The present invention relates to a method for producing and purifying citalopram of formula (I), wherein a compound of formula (II) in which Z is iodine, bromine, chlorine or CF- (CF) -SO-O-, n is 0, 1, 2, 3, 4, 5, 6, 7 or 8, is subjected to the reaction of cyanide exchange with a cyanide source; the resulting crude product, citalopram, is optionally subjected to some initial purification and subsequently treated with an agent forming an amide or similar amide group; the reaction mixture is then subjected to an acid / base wash and / or crystallization and recrystallization of citalopram to remove the resulting amides from the crude mixture of citalopram; and the resulting product, citalopram, is optionally further purified, processed, and / or isolated as a base or a pharmaceutically acceptable salt thereof. The international search report was published 2001.12.27. |
| priorityDate | 2000-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.