| abstract |
This invention relates to compositions of pharmaceutical combinations and methods comprising (-) - cis-6-phenyl-5- (4- (2-pyrrolidin-1-yl-ethoxy) -phenyl) -5,6,7,8-tetrahydronaphthalene -2-ol or its pharmaceutically acceptable salt and 2-amino-N- (2- (3a (R) -benzyl-2-methyl-3-oxo-2,3,3a, 4,6,7-hexahydropyrazolo- [ 4,3-c] pyridin-5-yl) -1 (R) -benzyloxymethyl-2-oxo-ethyl) -isobutyramide or its pharmaceutically acceptable salt, methods of using such compositions, and kits containing such compositions. These compositions are useful for treating musculoskeletal weakness, including osteoporosis, osteoporotic fracture, low bone mass, weakness, and low muscle mass. The international application was published along with an international search report. |