http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EA-200000708-A1
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-28 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-02 |
filingDate | 1998-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2000-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EA-200000708-A1 |
titleOfInvention | INSOLUBLE COMPOSITIONS USED TO REGULATE BLOOD GLUCOSE CONCENTRATION |
abstract | (57) The present invention relates to insoluble compositions comprising a protein selected from the group including insulin, insulin analogs and proinsulins; a derivative protein selected from the group consisting of a derivative of insulin, an analogue of a derivative of insulin and a derivative of insins; complexing compound; stabilizer hexamers and divalent metal cation. Insoluble compositions are suitable for both parenteral and non-parenteral route of administration in the treatment of hyperglycemia and diabetes. The microcrystalline forms of the insoluble precipitate are pharmaceutically analogous to the crystalline form of insulin with neutral protamine Heigdorn (NPH). Suspension drugs based on such insoluble compositions have been found to have unique controlled dissolution properties providing therapeutically beneficial glucodynamics compared to NPH insulin preparations. The international application was published along with an international search report. |
priorityDate | 1997-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 102.