abstract |
The purpose of the invention is to provide a process for obtaining an optically active pyrimidinamide derivative on an industrial scale. Compound (I) or a salt thereof is subjected to an asymmetric reduction reaction, the resulting compound (II) or a salt thereof is subjected to a deprotonation reaction, and the resulting compound (III) or a salt thereof is reacted with a compound (IV) or a salt thereof to obtain a compound (V) or salts thereof, wherein each symbol is as defined in the description of the present invention. |