abstract |
The invention relates to physically stable compositions in the form of an injectable aqueous solution, the pH of which is from 6.0 to 8.0, comprising at least a) basal insulin having an isoelectric point (pI) value of 5.8 to 8.5 , b) prandial insulin or gastrointestinal hormone and c) a copolyamino acid bearing carboxylate charges and at least one hydrophobic radical, said copolyamino acid consisting of glutamic or aspartic units selected from the copolyamino acids of formulas VII |