| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_66f3065b5b82b25dd8c6c09f2a19dd92 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-485
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D489-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-08 |
| filingDate |
2017-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac0a26bd60b6c0c4d733b64f5fa35faf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f9b87e2c5e1728b197b05a548e5bf93
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bcad0e73488e674b172678ab93f20ef0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a413f0f2b2cdde9618b218d81aaae11f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_68bbca506633f2a8f1017ce06cab8c24 |
| publicationDate |
2021-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EA-039290-B1 |
| titleOfInvention |
METHOD FOR ISOLATION AND PURIFICATION OF NALTREXONE |
| abstract |
The invention describes a process for purifying naltrexone base from a reaction mixture concentrated by evaporation and/or from mixtures containing naltrexone in the presence of other organic or inorganic substances by trituration and/or extraction and crystallization from cyclopentyl methyl ether (CPME), optionally from a mixture of cyclopentyl methyl ether and an organic solvent. With this method, high quality naltrexone (purity and content) is obtained, which can be used in a dosage form for parenteral use. |
| priorityDate |
2016-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |