| abstract |
The invention describes compounds of tetrahydropyrido [3,4-b] indol-1-yl with modulating activity or estrogen receptor function, having the structure of formula Ia as well as their stereoisomers, tautomers or pharmaceutically acceptable salts, and with the substituents and structural features described herein ... Also disclosed are pharmaceutical compositions and medicaments that include compounds of Formula I, as well as methods of using such estrogen receptor modulators alone and in combination with other therapeutic agents to treat diseases or conditions mediated or dependent on estrogen receptors. |