| abstract |
The invention relates to compounds containing analogs of unnatural nucleotides of the specified formula, which form unnatural base pairs during DNA polymerase mediated DNA replication or RNA polymerase mediated RNA transcription. Also disclosed are a composition for the formation of a non-naturally occurring base pair, a double-stranded oligonucleotide duplex, a method for carrying out site-specific functionalization of a double-stranded oligonucleotide duplex, and an oligonucleotide. |