| abstract |
The invention relates to antibodies against the transferrin receptor. In addition, the invention relates to the production of said antibody, namely the nucleic acid encoding it, and the host cell containing the specified nucleic acid. A pharmaceutical composition for the treatment of a neurological disorder is described, containing the indicated antibody, as well as its use for the treatment of a neurological disorder, the transfer of a compound associated with it through the blood-brain barrier, in a method for increasing the CNS exposure of a subject to a compound, in a method for increasing the retention of a compound in the CNS. |